Hypertension Takes Huge Toll in Developing Countries

(HealthDay News) -- Roughly 80 percent of high blood pressure-related deaths in the world occur in developing nations, a new study by New Zealand researchers shows.

Once regarded as a problem only in high-income countries, high blood pressure is now a global problem that affects both rich and poor nations, the researchers said.

The researchers calculated that 7.6 million premature deaths (about 13.5 percent of the worldwide total) and 92 million disability-adjusted life years (DALYS) -- 6 percent of the worldwide total -- among people over age 30 were caused by high blood pressure in 2001.

About 54 percent of strokes and 47 percent of heart disease cases were attributed to high blood pressure. About half of those cases occurred in people with hypertension (greater than 140 mm Hg systolic), while the remainder occurred in people with lesser degrees of high blood pressure.

In high-income countries, the proportion of premature deaths due to high blood pressure was 17.6 percent, compared to 12.9 percent in middle- and low-income nations. The proportion of DALYS due to high blood pressure in high-income nations was 9.3 percent, compared to 5.6 percent in middle- and low-income nations.

However, 80 percent of worldwide high blood pressure-related deaths occurred in middle- and low-income nations in eastern Europe and Asia, including China and India. More than one-third of all deaths in lower-income nations in Europe and central Asia were related to high blood pressure.

In high-income countries there were 1.39 million high blood pressure-related deaths; 418,000 stroke deaths; 668,000 heart disease deaths; 109,000 deaths due to hypertensive disease; and 197,000 deaths due to other cardiovascular diseases.

In low- and middle-income countries, there were 6.22 million high blood pressure-related deaths: 2.5 million stroke deaths; 2.68 million heart disease deaths; 598,000 hypertensive disease deaths; and 445,000 deaths due to other cardiovascular diseases.

"Most of the disease burden caused by high blood pressure is borne by low-income and middle-income countries, by people in middle age, and by people with lesser degrees of high blood pressure. Prevention and treatment strategies restricted to rich countries or individuals with hypertension will miss much blood pressure-related disease," wrote the University of Auckland researchers.

The study is published in this week's issue of The Lancet.

"Middle-income countries and low-income regions have a five times greater burden of disease than high-income regions, with access to less than 10 percent of the global treatment resource... This travesty cannot continue to be ignored by those most able to bring about change," Stephen MacMahon, of the George Institute for International Health at the University of Sydney in Australia, and his international colleagues, wrote in an accompanying editorial.

More information
The American Heart Association has more about high blood pressure.

Will Your New House Make You Sick?

The one we almost bought harbored cancer-causing gas and toxic mold. What buyers must check before their dream home turns into a nightmare
by Amy O'Connor

It was love at first sight. My husband and I couldn’t believe our luck. We met The One so early in our home-hunting process; the house was everything we’d ever dreamed of and more: neat and tidy, wrapped up in a bow.

Or so we thought when we offered asking price and had it accepted. We even bonded with the sweet little-old-lady seller, whose grandmotherly demeanor filled us with confidence about our impending purchase. I envisioned our closing date through a Vaseline-coated lens, complete with baked-from-scratch chocolate chip cookies provided by her and a group hug with both attorneys. Continue reading »

Calcium Scans Help Predict Coronary Risk

(HealthDay News) -- Scanning the heart arteries for calcium deposits can help predict future cardiac problems, a new study shows, but experts aren't sure that adding such scans to routine checkups would be worth the cost.

"It has been shown to be predictive" of potential heart trouble, said Dr. Diane Bild, deputy director of the division of prevention and population sciences at the U.S. National Heart, Lung, and Blood Institute, which funded the study. "Whether it is actually beneficial to the people who are screened has not been shown."

A calcium scan using computed tomography (CT) costs $300 to $600. These scans look for calcification -- hardening of the arteries caused by high blood fats and calcium deposits that can eventually cause blood vessel blockage. The scan is a potential competitor for much less expensive tests for coronary risk, such as blood cholesterol and blood pressure readings.

The new study involved more than 6,700 American men and women across a number of racial and ethnic groups -- white, black, Chinese, Hispanic -- who were followed for an average of 3.8 years. It found that the risk of a coronary event was nearly 10 times higher for those with the highest calcium deposit scores than for those with the lowest.

"This study was launched in 1999, a time when there was a lot of interest in whether this new test could predict coronary artery disease," Bild said. "A lot of studies have been done in predominantly white populations. This was one of our efforts to include minority groups."

The study does show that calcium scanning "modestly improves predictions over traditional risk factors," she said. "Several pieces of information are needed in order to understand whether this is clinically useful."

The findings are published in the March 27 issue of the New England Journal of Medicine.

The cost of such scans could be reduced, according to a statement from study lead author Dr. Robert Detrano, professor of radiological sciences at the University of California, Irvine, who is traveling in China. Scans have been done for just $30 in China, Detrano noted.

"It is mostly an issue of cost," said Dr. William S. Weintraub, chief of cardiology at the Christiana Health Care System, the largest health-care system in Delaware, who wrote an accompanying editorial in the journal. "It does add to our discrimination, but it costs a couple of hundred dollars and we're not sure how you use it."

Reducing the cost would make the test more usable, and "more epidemiological studies showing its value in risk prediction would be of great value," Weintraub said.

"But I'd be uncomfortable now with the idea of recommending this for everybody, or even defining a middle ground where we are unsure how we treat people so they get this first," he said.

A calcium scan also carries some risk, since it exposes a person to radiation, Bild noted. "It would be worth it if the benefit outweighed that risk," she said. "We don't clearly have both sides of that equation established."

More information
For more on coronary calcium scans, visit the U.S. Heart, Lung, and Blood Institute.

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A good marriage could be the key to better blood pressure

Story Highlights:

• Most happily married people had better blood pressure, study showed


• Doctor: Marital quality more important than just being married


• Spouses with low marital satisfaction had higher blood pressure than singles


• Study involved mostly white people; not known if race is a factor

NEW YORK (AP) -- A happy marriage is good for your blood pressure, but a stressed one can be worse than being single, a preliminary study suggests.

That second finding is a surprise because prior studies have shown that married people tend to be healthier than singles, said researcher Julianne Holt-Lunstad.

It would take further study to sort out what the results mean for long-term health, said Holt-Lunstad, an assistant psychology professor at Brigham Young University.

Her study was reported online Thursday by the Annals of Behavioral Medicine.

The study involved 204 married people and 99 single adults. Most were white, and it's not clear whether the same results would apply to other ethnic groups, Holt-Lunstad said.

Study volunteers wore devices that recorded their blood pressure at random times over 24 hours. Married participants also filled out questionnaires about their marriage.

Analysis found that the more marital satisfaction and adjustment spouses reported, the lower their average blood pressure was over the 24 hours and during the daytime.

But spouses who scored low in marital satisfaction had higher average blood pressure than single people did.

During the daytime, their average was about five points higher, entering a range that's considered a warning sign. (That result is for the top number in a blood pressure reading).

"I think this (study) is worth some attention," said Karen Matthews, a professor of psychiatry, psychology and epidemiology at the University of Pittsburgh. She studies heart disease and high blood pressure but didn't participate in the new work.

Few studies of the risk for high blood pressure have looked at marital quality rather than just marital status, she said.
It makes sense that marital quality is more important than just being married when it comes to affecting blood pressure, said Dr. Brian Baker, an associate professor of psychiatry at the University of Toronto.

Born to Be Obese?

(HealthDay News) -- The brain circuitry that controls appetite might be wired differently in some people, and that could predispose them to obesity, California researchers suggest.

The study was conducted in rats, not humans, and yet it could ultimately lead to novel obesity treatments, said Philip Smith, director of the Office of Obesity Research at the National Institute of Diabetes and Digestive and Kidney Diseases.

"It is not just about drugs that modify short-term appetite," he said, "there may be drugs that stimulate development of the appropriate neural pathways. So, it is an exciting, but very early, time in this field."

The study was published in the February issue of Cell Metabolism.

Sebastien Bouret, an assistant professor of neuroscience at the University of Southern California, and his colleagues examined neural circuits emanating from the appetite, hunger and body-weight control center of the brain -- the so-called arcuate nucleus of the hypothalamus (ARH) -- in a series of rats bred to be either prone to, or resistant to, obesity.

The team found fewer neural connections projecting from the ARH in obesity-prone animals than in their leaner counterparts. Surprisingly, Bouret said, this deficiency developed very early in life, before the animals became obese, and appeared to extend into adulthood.

"Somehow, these animals are programmed to become obese," Bouret said. "The obesity is hard-wired into the brain."

When the researchers then looked at why the brains of obese rats differed from their normal-weight counterparts, they found that the neurons from obesity-prone animals were less responsive to leptin, a hormone that controls the development of these circuits, and which also signals the body's energy status and controls metabolic rate.

"This paper presumes to say, these animals must be leptin-resistant, and that is why the pathways are not developing," said Smith.

But that doesn't mean they are doomed to a life of severe obesity, said Dr. Barbara Kahn, chief of the Division of Endocrinology, Diabetes and Metabolism at Beth Israel Deaconess Medical Center, in Boston. How they live their lives also matters.

"It is important not to 'blame' the obese person or imply that he/she is responsible for being obese," Kahn noted. "Having said that, reasonable, healthy caloric restriction and a safe and sustainable program of physical activity can help limit weight gain and often bring about some degree of weight loss. In addition, healthy eating and regular exercise can reduce the complications of obesity such as type 2 diabetes and cardiovascular disease."

At the same time, she added, not everyone can wear a size 4.

"There is a certain aspect of genetics that sets somebody in a certain range of possible body weights, and then how that person lives his or her life will determine whether they are at the bottom or top of the range," she explained.

Human obesity has both genetic and environmental roots. The rats used in this study, like most humans, developed obesity when fed a high-energy diet. On a normal diet, they were heavier than normal rats, but not yet obese.

"This is quite an exciting paper," said Smith, "because it links more closely to human behavior than most rodent models we have seen."

The findings also suggest a possible therapeutic approach to combating human obesity. If drugs could be designed to influence the formation of neural circuits during development and targeted to at-risk pregnancies, Smith said, "there is a good likelihood we could have successful interventions that improve the health of the mother, and which have a major impact on disease risk for the infant, during pregnancy."

A related study from Boston University researchers in the same journal found that bulking up muscle mass can lead to a general metabolic improvement in obese individuals. "Interventions designed to increase skeletal muscle mass in at-risk human populations may prove to be critical weapons in the fight against obesity and obesity-related comorbidities, including diabetes, heart disease, stroke, hypertension and cancer," an accompanying editorial stated.

More information
For more on obesity, visit the National Institute of Diabetes and Digestive and Kidney Diseases.

Hypertension Linked to Risk of Mild Cognitive Impairment

(HealthDay News) -- High blood pressure may be associated with increased risk for mild cognitive impairment, says a study by researchers at the Columbia University Medical Center in New York City.

Mild cognitive impairment, which causes learning and thinking difficulties, has "attracted increasing interest during the past years, particularly as a means of identifying the early stages of Alzheimer's disease as a target for treatment and prevention," the study authors wrote.

They followed 918 Medicare recipients aged 65 and older (average age 76.3) who were assessed every 18 months for an average of 4.7 years. None of the participants had mild cognitive impairment at the start of the study, but 334 of them developed the condition during the study period.

Of those, 160 developed amnestic mild cognitive impairment (which involves low scores on memory portions of neuropsychological tests), and 174 developed non-amnestic mild cognitive impairment. Hypertension was associated with an increased risk of all types of mild cognitive impairment, especially non-amnestic mild cognitive impairment, the researchers said.

The findings are published in the December issue of the Archives of Neurology.

"The mechanism by which blood pressure affects the risk of cognitive impairment or dementia remains unclear. Hypertension may cause cognitive impairment through cerebrovascular disease. Hypertension is a risk factor for subcortical white matter lesions found commonly in Alzheimer's disease. Hypertension may also contribute to a blood-brain barrier dysfunction, which has been suggested to be involved in the cause of Alzheimer's disease.

Other possible explanations for the association are shared risk factors," including the formation of cell-damaging compounds known as free radicals, the study authors wrote.

"Our findings support the hypothesis that hypertension increases the risk of incident mild cognitive impairment, especially non-amnestic mild cognitive impairment," the researchers concluded. "Preventing and treating hypertension may have an important impact in lowering the risk of cognitive impairment."

More information
The Alzheimer's Association has more about mild cognitive impairment.

Urine Test Results Can Point to Heart Dangers

(HealthDay News) -- Even a small amount of a protein called albumin in the urine of patients with stable coronary artery disease increases their risk of cardiovascular death, say U.S. researchers.

The findings from this study of almost 3,000 patients, age 50 and older, with stable coronary artery disease (CAD) have implications for assessing and perhaps treating patients with vascular disease.

The study was published in the current issue of the journal Circulation.

Albumin is normal and necessary in blood, but its presence in urine indicates leakage in the kidney filtration system and possible damage to cells that line the kidney's blood vessels, according to background information in the study.

"We found that virtually any degree of albuminuria, even albumin below the level we call microalbuminuria, placed a patient at significantly higher risk of cardiovascular events," lead author Dr. Scott D. Solomon, associate professor of medicine at Harvard Medical School and director of Noninvasive Cardiology at Brigham and Women's Hospital in Boston, said in a prepared statement.

He and his colleagues also found that the hypertension drug trandolapril (an ACE inhibitor) lowered albumin levels in patients' urine.

The findings of this study and previous research by the same team indicate that "we cardiologists need to pay more attention to kidney function in our patients, and we need to look at two aspects -- filtration and albuminuria," Solomon said.

"It is important for cardiologists to understand that these are not patients who will even come to dialysis or even necessarily see a nephrologist," he said. "But they do have mild kidney disease that puts them at increased risk for a cardiovascular event."

More information
The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about protein in urine.
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Weight Loss Can Control Hypertension

(HealthDay News) -- An Italian study has identified overweight as a direct cause of high blood pressure. And it also showed that up to half of overweight people can bring down blood pressure to healthy levels by weight reduction.

But the weight loss has to be achieved before the borderline to outright obesity is crossed, said Dr. Roberto Fogari, professor of medicine at the University of Pavia. He was to present the study findings Friday at the annual meeting of the American Heart Association's Council for High Blood Pressure Research, in Tucson, Ariz.

It's important that the study linked overweight to high blood pressure, which usually is described as "essential," a medical term meaning that the cause is unknown, Fogari said.

"The study suggests that, in many cases, hypertension [high blood pressure] is not essential," he said. "It is secondary to overweight. So, in the first stages of overweight, if we can induce people to reduce overweight, they can also avoid being treated for hypertension."

The study included 210 men and women whose body mass index [a ratio of weight to height] was between 25 and 29.9, indicating overweight but just short of the 30 mark of obesity. Their systolic blood pressure was between 140 and 159, and their diastolic pressure was between 90 and 99, indicating moderately high blood pressure.

An individualized low-calorie diet was designed for each study participant. Some also were prescribed orlistat, a drug that prevents fat from being metabolized.

After six months, 53 percent of the men and 49 percent of the women in the study achieved normal body weight, and a 5 percent reduction in blood pressure.

"The other 50 percent of those in the study already had abnormal changes in the vascular tree [blood vessel system], so that hypertension was no longer reversible by losing weight," Fogari said.

The implication for practicing physicians who see moderately overweight people with high blood pressure is that their first goal should be weight reduction, he said.

"Only after six months of trying to reduce the patient's weight can a decision be made about drug treatment," Fogari said.

Dr. Daniel W. Jones, dean of the University of Mississippi School of Medicine, and a spokesman for the American Heart Association, said the study finding "is not new news, but it is important news."

There have been a number of previous studies showing that weight loss can reduce blood pressure, Jones said. "But this is an increasingly important problem in societies around the world," he said. "Once you gain weight, you find it difficult to lose weight, which is why we focus so much on preventing obesity these days."

As for drug treatment of high blood pressure, about half of California adults diagnosed with hypertension do not take medication for it, another report presented at the same meeting found.

The study of 11,467 persons given a diagnosis of hypertension found that 49.4 percent were not taking drugs to reduce their blood pressure, said the report by researchers at the California Department of Public Health's Heart Disease and Stroke Prevention Program.

There were some bright spots in the picture. Compliance was more than five times higher for those who had seen a doctor in the past year than for those who had not. And the compliance rate was twice as high for persons with health insurance than the uninsured.

More information
For more on high blood pressure and what to do about it, turn to the American Heart Association.

Blood Pressure Drop During Bypass Might Impair Thinking

(HealthDay News) -- Patients who experience a blood pressure drop during bypass surgery may be at increased risk for a short-term dip in their cognitive abilities.

Researchers at the Johns Hopkins University School of Medicine in Baltimore studied 15 patients, aged 57 to 81, who were given cognitive tests before and then three to five days after they had coronary artery bypass graft (CABG) surgery.

All the patients had a decrease in mean arterial pressure (MAP) during surgery compared with their MAP before surgery. MAP provides doctors with an estimate of the blood pressure in various organs in the body.

The study found that patients whose MAP decreased by 27 millimeters of mercury or more had an average decrease of 1.4 points (out of a maximum of 30 points) on a standard cognitive test. Patients with a MAP decrease of less than 27 millimeters of mercury increased their scores by an average of one point.

Patients with a high MAP before their surgery were more likely to score lower on the cognitive test after their surgery.

The researchers also used MRI to examine the brains of 13 of the patients. They found that patients whose MAP decreased by more than 27 millimeters of mercury were 2.7 times more likely to show evidence of acute stroke.

The study was published online this week in the Archives of Neurology and is expected to be published in the August print issue.

The preliminary data from this small study suggests "that a substantial decrease in MAP from a patient's baseline may be a risk factor for short-term cognitive dysfunction," the study authors wrote. "This may be in part because of an increased risk for radiographic stroke."

Further studies are needed, the researchers said.

More information
The Alzheimer's Association has more about mild cognitive impairment.

Health Tip: Causes of Fainting

(HealthDay News) -- Fainting occurs due to a sudden drop in blood flow to the brain, resulting in brief loss of consciousness. Fainting can be accompanied by dizziness or nausea.

Here are some common triggers, courtesy of the U.S. National Library of Medicine:

• Straining during urination or a bowel movement.
• Excessive coughing.
• Standing for too long in the same position, or quickly standing up from a lying position.
• Severe pain, stress, fear or emotional distress.
• Excessive bleeding or dehydration.
• Medications used to treat conditions like high blood pressure, anxiety, allergies and nasal congestion.
• Use of drugs or alcohol.
• Low blood sugar.

No Clear Evidence Meditation Can Boost Health: Study

(HealthDay News) -- There's no definitive evidence that meditation eases health problems, according to an exhaustive review of the accumulated data by Canadian researchers.

"There is an enormous amount of interest in using meditation as a form of therapy to cope with a variety of modern-day health problems, especially hypertension, stress and chronic pain, but the majority of evidence that seems to support this notion is anecdotal, or it comes from poor quality studies," concluded researchers Maria Ospina and Kenneth Bond of the University of Alberta/Capital Health Evidence-based Practice Centre, in Edmonton.

They analyzed 813 studies focused on the impact of meditation on various conditions, including high blood pressure, cardiovascular disease and substance abuse.

Released Monday, the report looked at studies on five types of meditation practices: mantra meditation; mindfulness meditation; yoga, Tai Chi and Qi Gong.

Some of the studies suggested that certain types of meditation could help reduce blood pressure and stress and that yoga and other practices increased verbal creativity and reduced heart rate, blood pressure and cholesterol in healthy people.

However, the report authors said it isn't possible to draw any firm conclusions about the effects of meditation on health, because the existing studies are characterized by poor methodologies and other problems.

"Future research on meditation practices must be more rigorous in the design and execution of studies and in the analysis and reporting of results," Ospina said in a prepared statement.

Bond added that the new report doesn't prove that meditation has no therapeutic value, but it can inform medical practitioners that the "evidence is inconclusive regarding its effectiveness."

For the general public, the report "highlights that choosing to practice a particular meditation technique continues to rely solely on individual experiences and personal preferences, until more conclusive scientific evidence is produced," Ospina said.

The study was funded by the U.S. National Center for Complementary and Alternative Medicine in Bethesda, Md., part of the National Institutes of Health.

More information
The U.S. National Center for Complementary and Alternative Medicine has more about meditation for health purposes.

Don't Get Burned by Heat Stroke

(HealthDay News) -- Staying cool on hot summer days isn't just comfortable, it could save your life, according to the Pennsylvania Medical Society.

Heat stroke -- injury to internal organs caused by an excessively high body temperature -- is a serious and potentially deadly illness that can usually be prevented. Even so, it still happens all too frequently, experts say.

Many people recall the August 2001 death of Minnesota Viking's football player Korey Stringer.

He died after developing multi-organ system failure on a hot day. Athletes are particularly vulnerable to heat stroke -- especially football players, who wear body-covering uniforms and practice in the hottest temperatures -- but it can affect anyone.

Heat stroke can occur when you are in an extremely hot environment for a long period of time. It also happens when people overexert themselves on very hot days.

According to the Pennsylvania Medical Society, you should be alert to heat stroke on days when the relative humidity is at least 70 percent and temperatures are 95 degrees Fahrenheit and higher.

Other heat-related afflictions that may be a sign of looming heat stroke include heat cramps and heat exhaustion, which is characterized by pale, moist skin; headache; dizziness; nausea;

increased heart rate; low blood pressure; elevated temperature and profuse sweating.

The symptoms of heat stroke are more severe than those of heat exhaustion and may include:
Initial profuse sweating.
Hot, dry red skin.
High fever.
Vomiting.
Confusion.
Seizures during cooling.
Unconsciousness.
Sometimes lack of sweating, though athletes may perspire.
High body temperature (often 105 degrees or higher).
Anyone experiencing these symptoms should immediately seek emergency medical help.

Steps you can take to keep cool despite hot temperatures include:
Avoid overexertion.
Drink a quart of fluids an hour.
Wear loose, light-colored clothing made of light fabrics.
Wear a hat and sunblock.
Stay in the shade or indoors when possible.
Open windows and use fans and/or air conditioning; if you don't have air conditioning, go to a public place that does (a mall, library or movie theater).
Avoid dehydrating beverages such as caffeine and alcohol.

More information
The U.S. Centers for Disease Control and Prevention has more about extreme heat.

Certain ACE Inhibitors Cut Elderly Dementia Risk

(HealthDay News) -- Certain types of ACE inhibitor hypertension drugs may help cut the risk of dementia in older adults, say researchers at the Wake Forest University School of Medicine.
They analyzed data from the long-term Cardiovascular Health Study of almost 5,900 people over age 65 in the United States.

The researchers found that "centrally acting" ACE (angiotensin-converting enzyme) inhibitors may help reduce inflammation that might contribute to dementia.

Centrally acting ACE inhibitors are able to cross the blood-brain barrier and reach the brain.
"For older adults who are going to take an ACE inhibitor for blood pressure control, it makes sense for their doctors to prescribe one that goes into the brain," lead researcher Dr. Kaycee Sink, an assistant professor of internal medicine/gerontology, said in a prepared statement.

She and her colleagues found that for each year that people took centrally acting ACE inhibitors, they had a 50 percent lower rate of mental decline than people taking other kinds of hypertension drugs.

Mental decline was measured using the Modified Mini-Mental State Exam, which evaluates memory, language, abstract reasoning and other cognitive functions.

"These results suggest that there is more to treating blood pressure than achieving a goal of 140/80," Sink said. "Which drug you choose for blood pressure can have broader implications. We know that ACE inhibitors protect against heart failure and kidney failure, and now there is evidence that some of them may also protect against dementia."

The study was expected to be presented this weekend at the annual meeting of the American Geriatrics Society, in Seattle.

More information
The American Medical Association has more about dementia.

The Cardiovascular Cure

The Cardiovascular Cure

Written by John P. Cooke, M.D., Ph.D. and Judith Zimmer
Category: Medical - Diet Therapy
Publisher: BroadwayFormat: Trade Paperback, 336 pagesPub Date: August 2003
Price: $15.95
ISBN: 978-0-7679-0882-5 (0-7679-0882-1)

ABOUT THIS BOOK
The Cardiovascular Cure offers a groundbreaking approach to preventing heart attack and stroke by enhancing your body’s own natural defenses. Dr. John Cooke, head of Stanford Medical School’s vascular unit, has devised a powerful new method for fighting cardiovascular disease without bypass surgery or angioplasty.

Drawing on his own investigations, as well as Nobel Prize-winning research from a team of American scientists, Dr. Cooke provides heart patients with a diet, supplement, and exercise program that will help them feel better in as little as two weeks.

His program also works to prevent heart disease in those at risk.

In 1998, the Nobel Prize in Physiology or Medicine was awarded for the discovery of EDRF (endothelium-derived relaxing factor), a chemical produced in the lining of the blood vessels, which keeps them free of plaque. Dr. Cooke and other investigators have found that specific nutrients can enhance EDRF production and improve blood flow in people with high cholesterol, high blood pressure, diabetes, or other risk factors for heart disease.

This potentially life-saving book shows how anyone can achieve healthier blood vessels (the key to preventing heart disease). A two-week menu plan contains recipes that emphasize EDRF-enhancing foods, and there is detailed information on supplemental nutrients and vitamins that are useful in strengthening the cardiovascular system. Recipes from breakfast (Banana Date-Nut Bread; Blueberry Oat Pancakes; Pineapple Ginger or Tropical Smoothies; Pumpkin Muffins) to dinner (Moroccan Red Snapper; Chicken Wrap with Refried Beans; Soy-Glazed Salmon; Turkey Meatloaf) feature healthy fats found in fish, nuts, and olive oil.

There is also welcome news that red wine and chocolate can be good for you (there are recipes for Double Chocolate Cake and Chocolate Raspberry Surprise). The exercise program consists of the same therapeutic plans Dr. Cooke has prescribed for even his most severely ill patients, many of whom begin to walk and even exercise more vigorously without pain after two weeks. In addition, there are aerobic workouts designed for more active patients.

Dr. Cooke also provides state-of-the-art information (pro and con) on conventional drugs–from aspirin to beta blockers–and medical tests and procedures to further combat cardiovascular disease. With an introduction by Sir John Vane, a Nobel Prize-winning cardiovascular scientist, this book will provide anyone concerned about his or her cardiovascular health with new hope for a pain-free, disease-free life.

From the Hardcover edition.PRAISE“In The Cardiovascular Cure, Dr. Cooke has translated the research of our field into life-saving information that we can all use. If you really care about your cardiovascular health, you must read this book!”--Louis J. Ignarro, Ph.D., 1998 Nobel Laureate in Physiology or Medicine for the discovery of Nitric Oxide“This authoritative book appropriately points out why everyone should worry about the health of their endothelium and, better still, do something to protect it if it shows signs of damage.

Early identification and treatment of reduced nitric oxide release should be the preventive agenda for the new millenium.”--Jay N. Cohn, M.D., Professor of Medicine, University of Minnesota Medical School“This book should be read by all patients with heart disease as well as anyone at increased risk for a heart attack or stroke.

The comprehensive risk reduction program recommended by Dr. Cooke uses the most advanced research to help everyone improve the health of their blood vessels.” --William L. Haskell, Ph.D., Stanford Center for Research in Disease Prevention“The Cardiovascular Cure is a lucidly written description of EDRF and endothelial dysfunction.

Treatment with exercise and a diet rich in arginine, vitamins, and anti-oxidants is important to the many patients prone to develop heart attacks or stroke.”--Dr. Ferid Murad, M.D., Ph.D., Director of the Institute of Molecular Medicine at the University of Texas, 1998 Nobel Laureate in Physiology or Medicine“Helping yourself prevent a heart attack means knowing more than your ‘cholesterol count.’

In this clearly written book, Dr. Cooke introduces you to the important role played by the endothelium (the lining of your blood vessels) in this process, and what you can do to keep this vital organ as healthy as possible.”--Gerald Reaven, Professor of Medicine, Stanford University School of MedicineFrom the Hardcover edition.

ABOUT THIS AUTHORJOHN P. COOKE, M.D., Ph.D., is Associate Professor of Medicine and Director of the Section of Vascular Medicine at Stanford University’s Medical School. He trained at the Mayo Clinic, earning a Ph.D. in physiology there, and he was on the faculty of Harvard Medical School before he was recruited to Stanford to spearhead the program in Vascular Biology and Medicine.

He is a sought-after consultant and has served on numerous national and international committees dealing with cardiovascular diseases, including those of the American Heart Association and the National Heart, Lung and Blood Institute. JUDITH ZIMMER has been a medical journalist for more than fifteen years.

She has contributed to such publications as the New York Times, and Self and Fitness magazines, and she currently writes for academic medical centers in New York City.
From the Hardcover edition.

Calculator Helps Users Gauge Heart Attack Risk

(HealthDay News) -- A new online heart disease risk calculator that can help you understand and gauge your heart attack risk is available from the Mayo Clinic.

The risk calculator on MayoClinic.com asks several questions about your lifestyle and health and then determines your 10-year risk of a heart attack. The risk score is based on a number of factors, such as age, gender, tobacco use, cholesterol levels, and blood pressure.

You can find the risk calculator by heading to MayoClinic.com and looking under "Heart Disease Risk Factors," in the Web site's Heart Disease Center.

About one in 10 people with a risk level of 12 percent will have a heart attack or die of heart disease within the next 10 years, experts say.

Here are five heart disease prevention tips:

• Don't smoke or use tobacco products.
• Get exercise. Regular, moderately vigorous physical activity can reduce the risk of fatal heart disease by 25 percent. Combining physical activity with other positive lifestyle habits, such as maintaining a health weight, can provide even more heart health benefits.
• Eat a heart-healthy diet that includes plenty of fruits, vegetables, whole grains, and low-fat dairy products. Legumes, low-fat sources of protein and certain types of fish may also help reduce heart disease risk.
• Limit intake of saturated fats and trans fat.
• Watch your weight.
• Excess pounds can lead to conditions -- high blood pressure, high cholesterol and diabetes -- that increase the risk of heart disease.
• Get regular blood pressure and cholesterol screenings.
• High blood pressure and high cholesterol can damage your cardiovascular system, including your heart.

More information
There's more on reducing heart disease risk factors at the American Heart Association.

The biggest threat to the health of most Americans is the health-care system itself.

The biggest threat to the health of most Americans is the health-care system itself. More and more people are being drawn into treatment as a result of an astonishing increase in diagnoses, and ever-expanding definitions of what constitutes a disease.

This actually places these "patients" in greater danger than if they were simply left alone.
One problem is the medicalization of everyday life; everyday experiences such as insomnia, sadness, or twitchy legs are now being diagnosed as sleep disorder, depression, or restless leg syndrome. Especially troublesome is the medicalization of childhood, where trouble reading becomes dyslexia and unhappiness is deemed depression.

Another problem is the drive to diagnose disease early. Illnesses are now being identified in those with no symptoms, but who are merely "at risk." However, advanced technologies such as CT scans, ultrasounds, MRI and PET scans can detect subtle flaws that make practically everyone "at risk."

Meanwhile, at the same time, the definitions or diseases are expanding, as experts drop the thresholds for diagnosing diabetes, hypertension, osteoporosis and obesity. The level of cholesterol deemed "normal" has dropped several times. Merely because of these changes, more than half the population is now "diseased."

This epidemic of diagnoses has in turn led to an epidemic of treatments. And while not all treatments have benefits, almost all of them have harms. While the harms may outweigh the benefits for the severely ill, they can be far worse than the "disease" for those with only mild symptoms.

more informations at: dreddyclinic.com/

References:
New York Times January 2, 2007
Deseret News.com January 2, 2006

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As we age, our risk increases

With aging, arteries lose elasticity, often triggering elevated blood pressure.

Dietary abuses and a sedentary lifestyle further impact the health of our vascular system.

Recent Nobel Prize Winning Research is literally changing the landscape of cardiovascular health and reminding us of the power of the body to heal itself if provided the right nutrients.

How old is your heart?

It is well known that cardiovascular disease is the #1 cause of death and disability in the Western World.

• Nearly 62 million Americans have at least one type of cardiovascular disease: Arteriolosclerosis (hardening of the arteries) and high blood pressure are the leading risk factors.

Every 29 seconds, an American has what doctors call a coronary event.. . .such as a heart attack

• Death occurs from a coronary event every minute.
• A death occurs from a stroke every 3 minutes.

Digital Arterial Pulse-wave Analyzer

Digital Arterial Pulse-wave Analyzer
Over 1,000,000 people die each year due to heart disease and related illnesses.
500,000 women die every year from heart disease.

60% of youth are at risk for heart disease
Heart attacks kill more people than the next 9 causes of death combined!

The DPA is FDA approved medical equipment used for measurement and analysis of the pulse waveform. The pulse wave is the arterial pressure change that originates from the heartbeat and transmits through an artery.

The pulse wave is changed with the systolic power of heart and the vascular condition (the arterial elasticity, resistance, etc.), followed by the pulse wave. The information reflects the functional status of cardiovascular circulation. The DPA irradiates IR (infrared) to the fingertip and obtains pulse wave information with the light absorbing characteristics of HbO2 of arterial blood. The medical terminology for this measurement method is Plethysmogram (PTG).

The DPA, performs the automatic analysis of PTG (Plethysmogram), and also delivers secondary differentiated waveform (Accelerated Plethysmogram; (APG) and automatic analysis of it. The Analysis of PTG prepares the information of heart function, arterial elasticity, dilations, resistance, etc. The latest update on the DPA allows the product to analyse heart rate variability (HRV) from EKG data.

The analysis of APG prepares the information of arterial aging and is used for control of arterial-sclerosis and hypertension.

The benefit of the DPA is the ability to provide an early assessment of vascular disease and can profile individuals with respect to their cardiovascular health. Heart disease is a major cause of illness and death in North America. The repercussions cause high personal, community and health care costs.

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