Thursday, April 06, 2006

Why Take Celebrex to Treat Colon Cancer?

If Celebrex, the lone COX-2 inhibitor left on the market, more than doubles a patient's risks of a heart attack, why would anyone take it to prevent colon cancer? Perhaps, it's partly because drugmaker Pfizer told them so...

Pfizer partially funded one study along with the National Cancer Institute (NCI) and completely paid for a second one to investigate the value of Celebrex in preventing colon cancer.

In the former study involving more than 2,000 patients, less than half of those taking Celebrex developed polyps in their colons versus 60 percent of people taking a placebo. In the latter study, about a third of the patients taking 400 mg of Celebrex daily developed new colon polyps. Interestingly, nearly 8 percent of the patients taking Celebrex in the Pfizer-funded study suffered from heart-related side effects.

Due to those existing risks, researchers couldn't completely recommend Celebrex for patients with cardiovascular problems. That's why it pays to read between the lines and not take everything you read or hear on the news for face value. And, please understand, you don't need Celebrex or any other drug to lower your risk of cancer if you follow the major recommendations I outlined last year.

Medical News Today April 4, 2006
Yahoo News April 3, 2006

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